1242759-17-6

Basic information

• Product Name: 4-chloro-3,5-dimethylphenyl trifluoromethanesulfonate
• Synonyms: 4-chloro-3,5-dimethylphenyl trifluoromethanesulfonate
• CAS NO: 1242759-17-6
• Molecular Weight: 288.675
• Mol File: 1242759-17-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-chloro-3,5-dimethylphenyl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-3,5-dimethylphenyl trifluoromethanesulfonate(1242759-17-6)
• EPA Substance Registry System: 4-chloro-3,5-dimethylphenyl trifluoromethanesulfonate(1242759-17-6)

Safety Data

• Hazardous Substances Data: 1242759-17-6(Hazardous Substances Data)

Upstream product

• 421-83-0 trifluoromethane sulfonyl chloride 
• 88-04-0 4-Chloro-3,5-dimethylphenol 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 14994-16-2 1-chloro-4-fluoro-2,6-dimethylbenzene 

Relevant articles and documents

Nickel catalyzed decarboxylative alkylation of aryl triflates with anhydrides

Aliphatic acid anhydrides are the versatile building blocks and the new method for the conversion of anhydrides is thus of great significance. Herein, we report the decarboxylative alkylation of aryl triflates with aliphatic acid anhydrides via nickel catalysis. This novel method provides a facile access to construct Csp2-Csp3 bond. In addition, this method is compatible with a broad array of functional groups and exhibits good substrates scope.

Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2) and C(sp3) Coupling of C?Br, C?OTf, and C?Cl Bonds Enabled by a Single Palladium(I) Dimer

Full control over multiple competing coupling sites would enable straightforward access to densely functionalized compound libraries. Historically, the site selection in Pd0-catalyzed functionalizations of poly(pseudo)halogenated arenes has been unpredictable, being dependent on the employed catalyst, the reaction conditions, and the substrate itself. Building on our previous report of C?Br-selective functionalization in the presence of C?OTf and C?Cl bonds, we herein complete the sequence and demonstrate the first general arylations and alkylations of C?OTf bonds (in I dimer. This allowed the realization of the first general and triply selective sequential C?C coupling (in 2D and 3D space) of C?Br followed by C?OTf and then C?Cl bonds.

Remarkably effective phosphanes simply with a PPh2 moiety: Application to Pd-Catalysed cross-coupling reactions for tetra-ortho-substituted biaryl syntheses

Chemical equation presented Expanding the horizons of ArPPh2: New applications of triarylphosphane ligands are presented. The Pd-L1 and Pd-L2 complexes offer exceptionally high activity in Suzuki-Miyaura cross-couplings of aryl chlorides. The extremely congested synthesis of tetraortho-substituted biaryl compounds is achieved for the first time by simply using triarylphosphane ligands.