1243251-68-4

Basic information

• Product Name: C₂₃H₂₉N₃O₄
• CAS NO: 1243251-68-4
• Molecular Weight: 411.501
• Mol File: 1243251-68-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₉N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₉N₃O₄(1243251-68-4)
• EPA Substance Registry System: C₂₃H₂₉N₃O₄(1243251-68-4)

Safety Data

• Hazardous Substances Data: 1243251-68-4(Hazardous Substances Data)

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 1053168-75-4 C₁₃H₁₃N₃O₄ 
• 106-24-1 Geraniol 
• 64195-85-3 ethyl 2,4-dioxo-5-methylhexanoate 

Relevant articles and documents

New analogues of (E)-β-farnesene with insecticidal activity and binding affinity to aphid odorant-binding proteins

(E)-β-Farnesene is a strong and efficient alarm pheromone in most aphid species. However, applications in agriculture are prevented by its relatively high volatility, its susceptibility to oxidation and its complex and expensive synthesis. To develop novel compounds for aphid control, we have designed and synthesized analogues of (E)-β-farnesene, containing a pyrazole moiety present in several insecticides. Their structures have been confirmed by 1H NMR, elemental analysis, high-resolution mass spectroscopy and IR. Binding activities to three odorant-binding proteins (OBPs) of the pea aphid Acythosiphon pisum have been evaluated and correlated with their structures with reference to (E)-β-farnesene. Several derivatives were shown both to bind to A. pisum OBPs with a specificity similar to that of (E)-β-farnesene and to have aphicidal activity comparable to that of thiacloprid, a commercial insecticide. The compounds synthesized in this work represent new potential agents for aphid population control and provide guidelines to design analogues of (E)-β-farnesene endowed with both insecticidal and repellent activity for aphids.