124341-49-7

Basic information

• Product Name: 4-methoxy-1-nitro-2-(1-pyrrolidinyl)benzene
• Synonyms: 4-methoxy-1-nitro-2-(1-pyrrolidinyl)benzene
• CAS NO: 124341-49-7
• Molecular Weight: 222.244
• Mol File: 124341-49-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methoxy-1-nitro-2-(1-pyrrolidinyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-1-nitro-2-(1-pyrrolidinyl)benzene(124341-49-7)
• EPA Substance Registry System: 4-methoxy-1-nitro-2-(1-pyrrolidinyl)benzene(124341-49-7)

Safety Data

• Hazardous Substances Data: 124341-49-7(Hazardous Substances Data)

Upstream product

• 394-41-2 3-fluoro-4-nitrophenol 
• 123-75-1 pyrrolidine 
• 446-38-8 2-fluoro-4-methoxy-1-nitro-benzene 

Downstream Products

• 124341-46-4 (+/-)-(1α,2β,4α)-N-methyl-N-<4-methoxy-2-(1-pyrrolidinyl)cyclohexyl>-4-benzofuranacetamide 
• 124341-46-4 (+/-)-(1α,2β,4β)-N-methyl-N-<4-methoxy-2-(1-pyrrolidinyl)cyclohexyl>-4-benzofuranacetamide 
• 124341-46-4 (+/-)-(1β,2β,4α)-N-methyl-N-<4-methoxy-2-(1-pyrrolidinyl)cyclohexyl>-4-benzofuranacetamide 
• 124341-46-4 (+/-)-(1β,2β,4β)-N-methyl-N-<4-methoxy-2-(1-pyrrolidinyl)cyclohexyl>-4-benzofuranacetamide 

Relevant articles and documents

Tert-amino effect-promoted rearrangement of aryl isothiocyanate: A versatile approach to benzimidazothiazepines and benzimidazothioethers

A general and practical approach to benzimidazothiazepine and benzimidazothioether derivatives via an intramolecular nucleophilic addition/ring expansion rearrangement of aryl isothiocyanates promoted by the tert-amino effect has been developed. This reaction is catalyzed by low-cost camphorsulfonic acid and tolerates a broad substrate scope with complete atom economy. Structurally intriguing benzimidazothiazepine and benzimidazothioether products could be easily obtained by a simple operation in good to excellent yield (up to 98%).

Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents

Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents having very high kappa-opioid affinity and selectivity and potency and useful as analgesics, diuretics, antiinflammatory and psychotherapeutic agents are disclosed. Methods for making the com