124414-25-1

Basic information

• Product Name: 8-Bromo-4-p-tolyl-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid
• CAS NO: 124414-25-1
• Molecular Weight: 376.274
• Mol File: 124414-25-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-Bromo-4-p-tolyl-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Bromo-4-p-tolyl-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid(124414-25-1)
• EPA Substance Registry System: 8-Bromo-4-p-tolyl-2,3-dihydro-benzo[b][1,4]thiazepine-2-carboxylic acid(124414-25-1)

Safety Data

• Hazardous Substances Data: 124414-25-1(Hazardous Substances Data)

Upstream product

• 20972-36-5 (E)-4-oxo-4-(p-tolyl)but-2-enoic acid 
• 23451-95-8 2-amino-5-bromobenzenethiol 

Relevant articles and documents

Syntheses of 1,5-benzothiazepines: Part V - Synthesis of 2-carboxy-2,3-dihydro-4-(p-tolyl)-8-substituted-1,5-benzothiazepines

β-(p-Toluoyl)acrylic acid (2) reacts with 5-substituted 2-aminothiophenols (1a-e) in ethanol containing gl. acetic acid to give 2-carboxy-2,3-dihydro-4-(p-tolyl)-8-substituted-1,5-benzothiazepines (3a-e) in satisfactory yields.Their structure elucidation is based on elemental analyses and IR, PMR and mass spectral data.