124443-71-6Relevant articles and documents
SUBSTITUTED N-METHYL-N-(4-(PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES
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, (2008/06/13)
The present invention relates to novel substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamide derivatives of the formula STR1 stereoisomers thereof, and pharmaceutically acceptable salts thereof which are useful as histamine receptor antagonists and tachykinin receptor antagonists. Such antagonists are useful in the treatment of allergic rhinitis, including seasonal rhinitis and sinusitis; inflammatory bowel diseases, including Crohn's disease and ulcerative colitis; asthma; bronchitis; and emesis.
ANTIHISTAMINIC PIPERIDINYL BENZIMIDAZOLES
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, (2008/06/13)
The present invention is directed to a new class of piperidinyl benzimidazole antihistamines which can be described by the following formula: STR1 wherein Y is represented by CO or CHOH; m is an integer from 1 to 2; R is represented by C 1-4 alkyl, C 1-4