124469-06-3Relevant articles and documents
NEW CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF
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Page/Page column 50, (2012/01/14)
The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.
Stereoselective Syntheses of α-Substituted Cyclic Ethers and syn-1,3-Diols
Homma, Koichi,Takenoshita, Haruhiro,Mukaiyama, Teruaki
, p. 1898 - 1915 (2007/10/02)
In the presence of a catalytic amount of triphenylmethylium hexachloroantimonate or a catalyst system of antimony pentachloride, chlorotrimethylsilane and tin(II)iodide, α-substituted cyclic ethers are stereoselectively prepared from lactones by successiv
SUBSTITUTION REACTIONS OF 2-BENZENESULPHONYL CYCLIC ETHERS WITH SILYL ENOL ETHERS PROMOTED BY ALUMINIUM TRICHLORIDE
Brown, Dearg S.,Ley, Steven V.,Bruno, Maurizio
, p. 773 - 777 (2007/10/02)
Several cyclic ether 2-benzenesulphones were shown to react with silyl enol ethers in the presence of AlCl3 to give the corresponding alkylated products in good yield.Where substitution occured to give 2,6-disubstituted products there was a marked prefere