124477-12-9Relevant articles and documents
Attempts to improve the overall stereoselectivity of the Ireland-Claisen rearrangement
Chen, Chi-Li,Namba, Kosuke,Kishi, Yoshito
body text, p. 409 - 412 (2009/07/18)
(Chemical Equation Presented) With focus on the steric effects present in the transition states for the [3,3]-sigmatropic rearrangement, the substrate 5 has been designed to improve the overall stereoselectivity of the Ireland-Claisen rearrangement. Exper
Radical Cyclization Routes to Bridged Pyranosides as Precursors of Densely Functionalized Cycloalkanes
Alonso, R. A.,Vite, G. D.,McDevitt, R. E.,Fraser-Reid, B.
, p. 573 - 584 (2007/10/02)
Glycals derived from hexapyranoses permit the incorporation of iodine at C-2 as well as elaboration of an olefinic residue via the C-5-hydroxymethyl group.Radical cyclization of these functionalities leads to bicyclic systems whose bridge sizes depend on
CONVENIENT SYNTHESES OF SUBSTITUTED PYRANOID GLYCALS FROM THIOPHENYL GLYCOSIDES AND GLYCOSYL PHENYLSULFONES
Fernandez-Mayoralas, Alfonso,Marra, Alberto,Trumtel, Michel,Veyrieres, Alain,Sinay, Pierre
, p. 2537 - 2540 (2007/10/02)
A series of substituted thiophenyl glycosides and glycosyl phenylsulfones were converted in high yield into glycals after reductive lithiation with lithium naphthalenide, followed by elimination of the substituent at C-2.