124492-03-1

Basic information

• Product Name: N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-(S)-alanine-2'-benzothiazolylthio ester
• Synonyms: N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-(S)-alanine-2'-benzothiazolylthio ester
• CAS NO: 124492-03-1
• Molecular Weight: 428.576
• Mol File: 124492-03-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-(S)-alanine-2'-benzothiazolylthio ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-(S)-alanine-2'-benzothiazolylthio ester(124492-03-1)
• EPA Substance Registry System: N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-(S)-alanine-2'-benzothiazolylthio ester(124492-03-1)

Safety Data

• Hazardous Substances Data: 124492-03-1(Hazardous Substances Data)

Upstream product

• 114192-42-6 N-[(S)-1-carbethoxy-3-phenyl-propyl]-S-alaninoyl chloride hydrochloride 
• 149-30-4 2-Mercaptobenzothiazole 

Downstream Products

• 149-30-4 2-Mercaptobenzothiazole 
• 82586-54-7 quinapril benzyl ester 
• 87269-88-3 2--L-alanyl>-(1S,3S,5S)-2-azabicyclo<3.3.0>octane-3-carboxylic acid benzylester 
• 80876-01-3 trandolapril 
• 85441-61-8 quinapril 
• 87333-19-5 Ramipril 

Relevant articles and documents

NOVEL METHOD FOR PREPARATION OF CRYSTALLINE PERINDOPRIL ERBUMINE

A process for preparation of crystalline perindopril erbumine of formula (II) which exhibits the X-ray (powder) diffraction pattern like that shown in the figure. The process comprises reacting a solution of perindopril of formula (I), in a solvent selected from N, N-dimethylformamide or dimethyl acetals of lower aliphatic aldehydes and ketones with tertiary butylamine and crystallization of the erbumine salt thus obtained by heating the reaction mixture to reflux, filtering hot, cooling gradually to 20 oC to 30 oC, and further cooling to 0o C to 15 oC for 30 minutes to 1 hour and finally filtering off and drying the crystals.