1245623-49-7

Basic information

• Product Name: 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
• Synonyms: 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
• CAS NO: 1245623-49-7
• Molecular Weight: 307.66
• Mol File: 1245623-49-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one(1245623-49-7)
• EPA Substance Registry System: 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one(1245623-49-7)

Safety Data

• Hazardous Substances Data: 1245623-49-7(Hazardous Substances Data)

Upstream product

• 1228650-22-3 [3-(4-chlorophenyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]acetic acid 
• 1228650-21-2 ethyl N-({2-[(4-chlorophenyl)carbonyl]hydrazinyl}carbonyl)glycinate 
• 536-40-3 4-chlorobenzoic acid hydrazide 
• 1228650-24-5 5-(4-chlorophenyl)-4-(3,3,3-trifluoro-2,2-dihydroxypropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 

Downstream Products

• 1332502-31-4 5-(4-chlorophenyl)-2-{[1-(2-chlorophenyl)-1H-imidazol-4-yl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332502-32-5 5-(4-chlorophenyl)-2-{[1-(2-chlorophenyl)-1H-pyrazol-4-yl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332501-93-5 5-(4-chlorophenyl)-2-{[5-(2-chlorophenyl)-2-thienyl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxy-propyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332501-94-6 5-(4-chlorophenyl)-2-{[5-(2,3-dichlorophenyl)-2-thienyl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332502-09-6 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2-({2-[2-(trifluoromethyl)phenyl]-pyridin-4-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332502-11-0 5-(4-chlorophenyl)-2-{[2-(2,3-dichlorophenyl)pyridin-4-yl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332502-12-1 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2-({2-[2-(trifluoromethyl)phenyl]-pyrimidin-4-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332502-13-2 5-(4-chlorophenyl)-2-{[2-(2-chlorophenyl)pyrimidin-4-yl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332502-15-4 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2-({6-[2-(trifluoromethyl)phenyl]-pyrimidin-4-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332501-08-2 5-(4-chlorophenyl)-2-{[5-(2-chlorophenyl)-1,3,4-thiadiazol-2-yl]methyl}-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332501-97-9 5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2-({5-[2-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1332503-51-1 methyl 4-bromo-2-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)benzoate 
• 1332502-63-2 methyl 5-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-2'-(trifluoromethyl)biphenyl-2-carboxylate 
• 1332503-75-9 2-[(3-bromophenyl)sulfonyl]-5-(4-chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 

Relevant articles and documents

BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF

The present application relates to novel bisaryl-linked 5-aryl-1,2,4-triazolone derivatives, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.