1245649-56-2

Basic information

• Product Name: 6-Bromo-2-cyclopropylisoindolin-1-one
• Synonyms: 6-Bromo-2-cyclopropylisoindolin-1-one;6-Bromo-2-cyclopropyl-2,3-dihydro-isoindol-1-one
• CAS NO: 1245649-56-2
• Molecular Formula: C11H10BrNO
• Molecular Weight: 252.1072
• Mol File: 1245649-56-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 385.138 °C at 760 mmHg
• Flash Point: 186.725 °C
• Appearance: /
• Density: 1.69 g/cm³
• CAS DataBase Reference: 6-Bromo-2-cyclopropylisoindolin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-2-cyclopropylisoindolin-1-one(1245649-56-2)
• EPA Substance Registry System: 6-Bromo-2-cyclopropylisoindolin-1-one(1245649-56-2)

Safety Data

• Hazardous Substances Data: 1245649-56-2(Hazardous Substances Data)

Upstream product

• 79670-17-0 methyl 2-bromomethyl-5-bromobenzoate 
• 765-30-0 Cyclopropylamine 

Relevant articles and documents

Nucleoside analogs useful as PRMT5 inhibitors

The invention relates to the technical field of biological medicines, and particularly discloses a nucleoside analogue used as a PRMT5 inhibitor. According to the nucleoside analogue as shown in the formula (I) or the pharmaceutically acceptable salt of the nucleoside analogue, the nucleoside analogue or the pharmaceutically acceptable salt of the nucleoside analogue shows relatively high inhibition on the activity of PRMT5 and can be used for preventing and/or treating PRMT5-mediated diseases, and the PRMT5-mediated diseases comprise cell abnormal proliferative diseases.