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124623-37-6

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124623-37-6 Usage

Preparation

Preparation by successively adding propionitrile and aluminium chloride to a solution of boron trichloride and 3-fluoro-4-methoxyaniline in benzene under nitrogen and refluxing the mixture obtained for 8 h (70%).

Check Digit Verification of cas no

The CAS Registry Mumber 124623-37-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,6,2 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 124623-37:
(8*1)+(7*2)+(6*4)+(5*6)+(4*2)+(3*3)+(2*3)+(1*7)=106
106 % 10 = 6
So 124623-37-6 is a valid CAS Registry Number.

124623-37-6Downstream Products

124623-37-6Relevant articles and documents

Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them

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, (2008/06/13)

A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.

Comptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues

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Example 28, (2008/06/13)

The compound of the formula wherein the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts which are useful for the treatment of viral infections, parasitic diseases and the treatment of cancer.

Synthesis and antitumor activity of 20(S)-camptothecin derivatives. A-ring-substituted 7-ethylcamptothecins and their E-ring-modified water-soluble derivatives

Yaegashi,Sawada,Nagata,Furuta,Yokokura,Miyasaka

, p. 2518 - 2525 (2007/10/02)

Twenty-six novel A-ring-modified 7-ethylcamptothecins (6) were synthesized by Friedlander's condensation of the chiral tricyclic ketone (5) with aminopropiophenones (4). The compounds substituted with fluorine at the 11 position showed strong cytotoxicity

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