1246370-32-0Relevant articles and documents
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: Involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation
Kudo, Fumitaka,Motegi, Atsushi,Mizoue, Kazutoshi,Eguchi, Tadashi
, p. 1574 - 1582 (2010)
FD-891 is a 16-membered cytotoxic antibiotic macrolide that is especially active against human leukemia such as HL-60 and Jurkat cells. We identified the FD-891 biosynthetic (gfs) gene cluster from the producer Streptomyces graminofaciens A-8890 by using