1246457-26-0Relevant articles and documents
Iodination of verapamil for a stronger induction of death, through GSH efflux, of cancer cells overexpressing MRP1
Barattin, Régis,Perrotton, Thomas,Trompier, Doriane,Lorendeau, Doriane,Pietro, Attilio Di,D'Hardemare, Amaury Du Moulinet,Baubichon-Cortay, Hélne
experimental part, p. 6265 - 6274 (2010/10/19)
The multidrug resistance protein 1 (MRP1), involved in multidrug resistance (MDR) of cancer cells, was found to be modulated by verapamil, through stimulation of GSH transport, leading to apoptosis of MRP1-overexpressing cells. In this study, various iodi