124667-65-8

Basic information

• Product Name: {(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-4-oxo-azetidin-1-yl}-acetic acid allyl ester
• Synonyms: {(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-4-oxo-azetidin-1-yl}-acetic acid allyl ester
• CAS NO: 124667-65-8
• Molecular Weight: 512.743
• Mol File: 124667-65-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-4-oxo-azetidin-1-yl}-acetic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-4-oxo-azetidin-1-yl}-acetic acid allyl ester(124667-65-8)
• EPA Substance Registry System: {(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-4-oxo-azetidin-1-yl}-acetic acid allyl ester(124667-65-8)

Safety Data

• Hazardous Substances Data: 124667-65-8(Hazardous Substances Data)

Upstream product

• 40630-84-0 allyl bromoacetate 
• 115026-51-2 (S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-[(R)-2-(4,4-dimethyl-2-thioxo-oxazolidin-3-yl)-1-methyl-2-oxo-ethyl]-azetidin-2-one 

Relevant articles and documents

SYNTHESIS OF 1-β-METHYLCARBAPENEM KEY INTERMEDIATES INVOLVING THE LABILE ACYL AUXILIARY 4,4-DIMETHYL-1,3-OXAZOLIDINE-2-THIONE

A convenient synthesis of 1-β-methylcarbapenem key intermediates based on the facile displacement of the 4,4-dimethyl-1,3-oxazolidine-2-thione auxiliary of 5 is described.