124700-41-0 Usage
Description
2-Fluoro-5-iodobenzoic acid is an organic compound characterized by the presence of a fluorine atom at the 2nd position and an iodine atom at the 5th position on a benzoic acid structure. It is a white solid with specific chemical properties that make it a valuable precursor in the synthesis of various compounds and reagents.
Uses
Used in Mass Spectrometry:
2-Fluoro-5-iodobenzoic acid is used as a precursor molecule for generating Electron Transfer Dissociation (ETD) reagents via Electrospray Ionization (ESI) followed by Collision-Induced Dissociation (CID). This application is crucial in the field of mass spectrometry for the analysis and identification of biomolecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Fluoro-5-iodobenzoic acid serves as a starting material in the synthesis of 3,6-disubstituted 2-pyridinecarboxamide, which are known as GK activators. These compounds have potential therapeutic applications, particularly in the treatment of various diseases and conditions.
Used in Chemical Synthesis:
2-Fluoro-5-iodobenzoic acid is also utilized as an intermediate in the synthesis of other complex organic molecules, contributing to the development of new compounds with diverse applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 124700-41-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,7,0 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 124700-41:
(8*1)+(7*2)+(6*4)+(5*7)+(4*0)+(3*0)+(2*4)+(1*1)=90
90 % 10 = 0
So 124700-41-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H4FIO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,(H,10,11)
124700-41-0Relevant articles and documents
Synthesis method of 2-halogen-5-iodobenzoic acid
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Paragraph 0043-0047, (2019/09/17)
The invention discloses a synthesis method of 2-halogen-5-iodobenzoic acid. The synthesis method comprises steps as follows: o-halogen benzoic acids are subjected to one-step iodo treatment in an iodio reagent, and 2-halogen-5-iodobenzoic acid is obtained. Aftertreatment comprises steps as follows: a reaction liquid is poured into a cold reductive water solution and quenched, a solvent is evaporated to dryness, recrystallization and filtration are performed, and a product can be obtained. The method is short in reaction route, simple to operate, environmentally friendly, safer and more economical and has broad application prospects.
Novel HIV-1 integrase inhibitors derived from quinolone antibiotics
Sato, Motohide,Motomura, Takahisa,Aramaki, Hisateru,Matsuda, Takashi,Yamashita, Masaki,Ito, Yoshiharu,Kawakami, Hiroshi,Matsuzaki, Yuji,Watanabe, Wataru,Yamataka, Kazunobu,Ikeda, Satoru,Kodama, Eiichi,Matsuoka, Masao,Shinkai, Hisashi
, p. 1506 - 1508 (2007/10/03)
The viral enzyme integrase is essential for the replication of human immunodeficiency virus type 1 (HIV-1) and represents a remaining target for antiretroviral drugs. Here, we describe the modification of a quinolone antibiotic to produce the novel integr
4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents
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, (2008/06/13)
This invention provides compounds of formula I; which are useful as antiviral agents.
