124782-04-3

Basic information

• Product Name: methyl (2S,3R)-3--2-hydroxy-4-phenylbutanoate
• Synonyms: methyl (2S,3R)-3--2-hydroxy-4-phenylbutanoate
• CAS NO: 124782-04-3
• Molecular Weight: 343.379
• Mol File: 124782-04-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: methyl (2S,3R)-3--2-hydroxy-4-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2S,3R)-3--2-hydroxy-4-phenylbutanoate(124782-04-3)
• EPA Substance Registry System: methyl (2S,3R)-3--2-hydroxy-4-phenylbutanoate(124782-04-3)

Safety Data

• Hazardous Substances Data: 124782-04-3(Hazardous Substances Data)

Upstream product

• 137028-93-4 (4R,5S)-4-benzyl-3-benzyloxycarbonyl-2,2-dimethyl-oxazolidine-5-carboxylic acid methyl ester 
• 23402-69-9 lithium diphenylcuprate 
• 152897-52-4 (S)-5-<(S)-2-phenyl-1-(N-tosylamino)ethyl>-1,3-dioxolane 
• 152897-53-5 (2S,3R)-3-benzyloxycarbonylamino-2-hydroxy-4-phenyl-1-butanol 
• 95105-20-7 (2S,3R)-3-amino-4-phenylbutane-1,2-diol 
• 591-51-5 phenyllithium 
• 63219-70-5 N-(benzyloxycarbonyl)-D-phenylalaninal 

Downstream Products

• 137028-93-4 (4R,5S)-4-benzyl-3-benzyloxycarbonyl-2,2-dimethyl-oxazolidine-5-carboxylic acid methyl ester 
• 144676-38-0 epi-Aminodeoxybestatin 
• 144676-53-9 (2R,3R)-2-Azido-3-(benzyloxycarbonylamino)-4-phenylbutanoic Acid Methyl Ester 
• 144676-55-1 (2R,3R)-2-Azido-3-(benzyloxycarbonylamino)-4-phenylbutanoic Acid 
• 137028-96-7 (4'R,5'S)-4-(4'-benzyl-3'-benzyloxycarbonyl-2',2'-dimethyl-oxazolidine-5'-yl)-2-isobutyl-2-methoxycarbonyl-4-oxobutyric acid methyl ester 
• 137028-95-6 (4'R,5'S)-4-(4'-benzyl-3'-benzyloxycarbonyl-2',2'-dimethyl-oxazolidine-5'-yl)-2-methoxycarbonyl-4-oxobutanoic acid methyl ester 
• 137028-94-5 (4R,5S)-4-benzyl-3-benzyloxycarbonyl-5-(chloromethyl)carbonyl-2,2-dimethyl-oxazolidine 
• 150744-82-4 (4R,5S)-4-benzyl-3-benzyloxycarbonyl-2,2-dimethyl-oxazolidine-5-carboxylic acid 
• 144676-50-6 (2S,3R)-3-(Benzyloxycarbonylamino)-2-methylsulfonyloxy-4-phenylbutanoic Acid Methyl Ester 
• 59969-65-2 (2S,3R)-3-benzyloxycarbonylamino-2-hydroxy-4-phenyl-butanoic acid 
• 100564-98-5 (4R,5S)-4-benzyl-2-oxo-5-oxazolidinecarboxylic acid 

Relevant articles and documents

Synthesis of methyl 3-amino-2-hydroxy-4-phenylbutanoates, important core intermediates for peptide mimics possessing biological activities

Core intermediates for the synthesis of anti-cancer agents, inhibitors of aminopeptidases and HIV proteases, 3-amino-2-hydroxy-4-phenylbutanoates were synthesized by using H-C(CN)2O-SiR3 as a key reagent.

Ring opening of optically active cis-disubstituted aziridino alcohols: An enantiodivergent synthesis of functionalized amino alcohol derivatives

Ring-opening reactions of optically active cis-disubstituted aziridino alcohols have been investigated. Regio- and stereo-selective ring opening took place with internal and external nucleophiles. Unusual amino acids derivatives (14) and (15), the key synthetic intermediates for bestatin and related peptides, have been prepared. n.

An improved one-pot method for the stereoselective synthesis of the (2S,3R)-3-amino-2-hydroxy acids: Key intermediates for bestatin and amastatin

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