1248456-74-7Relevant articles and documents
2-pyridyl substituted imidazoles as therapeutic ALK5 and/or ALK4 inhibitors
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Page/Page column 29, (2012/01/04)
This invention relates to 2-pyridyl substituted imidazoles which are inhibitors of the transforming growth factor-β (TGF-β) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.