1248501-62-3

Basic information

• Product Name: C₁₇H₁₆⁽²⁾H₃N₅O₃
• Synonyms: C₁₇H₁₆⁽²⁾H₃N₅O₃
• CAS NO: 1248501-62-3
• Molecular Weight: 344.346
• Mol File: 1248501-62-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₆⁽²⁾H₃N₅O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₆⁽²⁾H₃N₅O₃(1248501-62-3)
• EPA Substance Registry System: C₁₇H₁₆⁽²⁾H₃N₅O₃(1248501-62-3)

Safety Data

• Hazardous Substances Data: 1248501-62-3(Hazardous Substances Data)

Upstream product

• 1248504-52-0 C₂₂H₂₄⁽²⁾H₃N₅O₅ 
• 1248504-51-9 5-(methoxy-d₃)pyrazine-2-carboxylic acid 
• 36070-80-1 5-chloropyrazinoic acid 
• 33332-25-1 methyl 5-chloropyrazine-2-carboxylate 

Relevant articles and documents

ISOTHIOUREA DERIVATIVES OR ISOUREA DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY

The present invention provides, for example, a compound of the following formula (I): wherein R1 is substituted amino and the like, R2 is halogen and the like, R3 is substituted or unsubstituted lower alkyl and the like, RA and RB are each independently hydrogen, substituted or unsubstituted lower alkyl and the like, RC and RD are each independently hydrogen, substituted or unsubstituted lower alkyl, or RC and RD together with the carbon atom to which they are attached may form a substituted or unsubstituted carbocycle, and ring A is a carbocycle or a heterocycle, its pharmaceutically acceptable salt, or a solvate thereof as a therapeutic agent for diseases induced by production, secretion and/or deposition of amyloid-βproteins.