124949-16-2

Basic information

• Product Name: (Z)-N-Benzyl-3-(benzylthio)but-2-enamide
• Synonyms: (Z)-N-Benzyl-3-(benzylthio)but-2-enamide
• CAS NO: 124949-16-2
• Molecular Weight: 297.421
• Mol File: 124949-16-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-N-Benzyl-3-(benzylthio)but-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-Benzyl-3-(benzylthio)but-2-enamide(124949-16-2)
• EPA Substance Registry System: (Z)-N-Benzyl-3-(benzylthio)but-2-enamide(124949-16-2)

Safety Data

• Hazardous Substances Data: 124949-16-2(Hazardous Substances Data)

Upstream product

• 10128-99-1 3-benzyl-6-methyl-[1,3]oxazine-2,4-dione 
• 32894-07-8 S-benzyl thioacetimidate hydrochloride 

Downstream Products

• 124949-15-1 (E)-N-Benzyl-3-(benzylthio)but-2-enamide 

Relevant articles and documents

Heterocyclic Transformations. Part 3. Thiolate Ion-induced Transformations of 6-Methyl-1,3-oxazine-2,4(3H)-diones to 3-(Alkyl/arylthio)but-2-enamides

Thiolate ions generated under phase-transfer catalytic conditions react exclusively at C-6 of 3-alkyl-6-methyl-1,3-oxazine-2,4(3H)-diones to give (E)- and (Z)-3-(alkylthio)but-2-enamides.With binucleophiles having at least one thiol group, the E+Z thiobutenamides are initially formed and their further transformation depends on the nature on the second nucleophile.The bulk of the N-3 substituent of the oxazine and the thiol exercise steric control on the rate and mode of the reaction.