124952-36-9 Usage
Description
3'-Hydroxywarfarin, also known as (S)-3'-Hydroxywarfarin, is the S-enantiomer of the 3'-hydroxyl metabolite of Warfarin (W498500). It is a significant compound derived from the metabolism of Warfarin, a widely used anticoagulant medication. The S-enantiomer is known to have a more potent anticoagulant effect compared to its R-enantiomer, making it a crucial component in the study and development of anticoagulant therapies.
Uses
Used in Pharmaceutical Industry:
3'-Hydroxywarfarin is used as an active metabolite for its anticoagulant properties. The compound plays a vital role in the development of novel anticoagulant drugs, as it possesses a more potent effect than the parent compound, Warfarin. This makes it a promising candidate for the treatment of various blood clot-related conditions, such as deep vein thrombosis, pulmonary embolism, and atrial fibrillation.
Used in Research and Development:
3'-Hydroxywarfarin is used as a research compound for studying the mechanisms of action and the pharmacokinetics of Warfarin. Understanding the properties and effects of this metabolite can help researchers develop more effective and safer anticoagulant medications. Additionally, it can be used to investigate the role of enantiomers in drug action and their potential impact on therapeutic outcomes.
Used in Drug Interaction Studies:
3'-Hydroxywarfarin is used as a tool in studying drug interactions involving Warfarin. Since the S-enantiomer has a more potent effect, it can help researchers understand how other medications or substances may interact with Warfarin, potentially leading to adverse effects or altered efficacy. This information is crucial for healthcare providers to make informed decisions regarding the use of Warfarin in combination with other medications.
Check Digit Verification of cas no
The CAS Registry Mumber 124952-36-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,5 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 124952-36:
(8*1)+(7*2)+(6*4)+(5*9)+(4*5)+(3*2)+(2*3)+(1*6)=129
129 % 10 = 9
So 124952-36-9 is a valid CAS Registry Number.
124952-36-9Relevant articles and documents
Organocatalytic enantioselective michael addition of 4-hydroxycoumarin to α,β-unsaturated ketones: a simple synthesis of warfarin
Dong, Zhenhua,Wang, Lijia,Chen, Xiaohong,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
experimental part, p. 5192 - 5197 (2010/01/11)
A type of C2-symmetric secondary amine amide catalysts were developed for the asymmetric Michael addition of Ahydroxycoumarin to α,ss-unsaturated ketones. A series of important biologically and pharmaceutically active compounds were obtained in
