124980-93-4 Usage
Description
(S)-3-(4-fluorophenyl)-2-hydroxypropionic acid, also known as dexfenfluramine, is a chemical compound that was once utilized as an appetite suppressant to assist in weight loss. It operates by increasing serotonin levels in the brain, which can result in a sensation of fullness and a decrease in appetite.
Uses
Used in Pharmaceutical Industry:
Dexfenfluramine was used as an appetite suppressant for weight loss management due to its ability to increase serotonin levels in the brain, leading to feelings of fullness and reduced appetite.
However, it is important to note that dexfenfluramine was withdrawn from the market due to safety concerns, specifically its association with heart valve damage and pulmonary hypertension (high blood pressure in the lungs). Consequently, dexfenfluramine is no longer utilized for weight loss and is considered a prohibited substance for medical use.
Check Digit Verification of cas no
The CAS Registry Mumber 124980-93-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,8 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 124980-93:
(8*1)+(7*2)+(6*4)+(5*9)+(4*8)+(3*0)+(2*9)+(1*3)=144
144 % 10 = 4
So 124980-93-4 is a valid CAS Registry Number.
124980-93-4Relevant articles and documents
Biocatalytic racemization of aliphatic, arylaliphatic, and aromatic α-hydroxycarboxylic acids
Glueck, Silvia M.,Pirker, Monika,Nestl, Bettina M.,Ueberbacher, Barbara T.,Larissegger-Schnell, Barbara,Csar, Katrin,Hauer, Bernhard,Stuermer, Rainer,Kroutil, Wolfgang,Faber, Kurt
, p. 4028 - 4032 (2007/10/03)
Biocatalytic racemization of a range of aliphatic, (aryl)aliphatic, and aromatic α-hydroxycarboxylic acids was accomplished by using whole resting cells of a range of Lactobacillus spp. The mild (physiological) reaction conditions ensured an essentially "clean" isomerization in the absence of side reactions, such as elimination or decomposition. Whereas straight-chain aliphatic 2-hydroxy-carboxylic acids were racemized with excellent rates (up to 85% relative to lactate), steric hindrance was observed for branched-chain analogues. Good rates were observed for aryl-alkyl derivatives, such as 3-phenyllactic acid (up to 59%) and 4-phenyl-2-hydroxybutanoic acid (up to 47%). In addition, also mandelate and its o-chloro analogue were accepted at a fair rate (45%). This biocatalytic racemization represents an important tool for the deracemization of a number of pharmaceutically important building blocks.
