124980-97-8

Basic information

• Product Name: (S)-methyl-2-hydroxy-3-(4-fluorophenyl)propionate
• Synonyms: (S)-methyl-2-hydroxy-3-(4-fluorophenyl)propionate
• CAS NO: 124980-97-8
• Molecular Weight: 198.194
• Mol File: 124980-97-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-methyl-2-hydroxy-3-(4-fluorophenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl-2-hydroxy-3-(4-fluorophenyl)propionate(124980-97-8)
• EPA Substance Registry System: (S)-methyl-2-hydroxy-3-(4-fluorophenyl)propionate(124980-97-8)

Safety Data

• Hazardous Substances Data: 124980-97-8(Hazardous Substances Data)

Upstream product

• 1132-68-9 L-4-fluorophenylalanine 
• 74-88-4 methyl iodide 

Downstream Products

• 249736-11-6 (S)-3-(4-Fluoro-phenyl)-2-hydroxy-propionic acid allyl ester 
• 249736-19-4 (E)-(S)-5-[(S)-1-(2,4-Dimethoxy-benzyl)-2-oxo-pyrrolidin-3-yl]-4-((S)-3-(4-fluoro-phenyl)-2-{(S)-3-methyl-2-[(5-methyl-isoxazole-3-carbonyl)-amino]-butyryloxy}-propionylamino)-pent-2-enoic acid ethyl ester 
• 249736-13-8 (E)-(S)-4-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyryloxy)-3-(4-fluoro-phenyl)-propionylamino]-6-(trityl-carbamoyl)-hex-2-enoic acid ethyl ester 
• 249736-18-3 (S)-3-Methyl-2-[(5-methyl-isoxazole-3-carbonyl)-amino]-butyric acid (S)-1-allyloxycarbonyl-2-(4-fluoro-phenyl)-ethyl ester 
• 249736-12-7 (S)-2-tert-Butoxycarbonylamino-3-methyl-butyric acid (S)-1-allyloxycarbonyl-2-(4-fluoro-phenyl)-ethyl ester 
• 394217-83-5 (S)-3-Methyl-2-[(5-methyl-isoxazole-3-carbonyl)-amino]-butyric acid (S)-1-carboxy-2-(4-fluoro-phenyl)-ethyl ester 
• 394217-82-4 (S)-2-tert-Butoxycarbonylamino-3-methyl-butyric acid (S)-1-carboxy-2-(4-fluoro-phenyl)-ethyl ester 

Relevant articles and documents

Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors

Novel tripeptidyl C-terminal Michael acceptors with an ester replacement of the P2-P3 amide bond were investigated as irreversible inhibitors of the human rhinovirus (HRV) 3C protease (3CP). When screened against HRV serotype-14 the best compound was shown to have very good 3CP inhibition (kobs/[I]=270,000 M-1 s-1) and potent in vitro antiviral activity (EC50=7.0 nM).