125031-58-5Relevant articles and documents
A New Route to 2-Amino- or 2-Hydroxy-3-pyridinecarboxylic Acid Derivatives
Ito, Kunio,Yokokura, Seiichi,Miyajima, Shingo
, p. 773 - 778 (2007/10/02)
Schiff's bases derived from ketones and t-butylamine (1) reacted with methyl methoxymethylenemalonate to give 2-hydroxy-3-pyridinecarboxylates.Similarly, treatment of 1 with ethoxymethylenemalononitrile gave 2-amino-3-pyridinecarbonitriles.Compounds 1 on reaction with ethyl 2-cyano-3-ethoxypropenoate afforded 2-amino-3-pyridinecarboxylates.