1250377-76-4

Basic information

• Product Name: C₂₄H₂₃FN₄O₂
• CAS NO: 1250377-76-4
• Molecular Weight: 418.471
• Mol File: 1250377-76-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₃FN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₃FN₄O₂(1250377-76-4)
• EPA Substance Registry System: C₂₄H₂₃FN₄O₂(1250377-76-4)

Safety Data

• Hazardous Substances Data: 1250377-76-4(Hazardous Substances Data)

Upstream product

• 65786-13-2 2'-hydroxy-4-dimethylaminochalcone 

Relevant articles and documents

Chalconsemicarbazone: A new scaffold for antiepileptic drug discovery

During our investigation in the area of epileptic drug discovery, we have identified that the available conventional antiepileptic drugs are effective in 60-80% patients and in specific type of seizures and having various undesirable side effects. But in present time a new class aryl semicarbazone is emerged as new pharmacophore in epileptic drug discovery having broad spectrum activity. On the bases of work done in this area we have applied hybridization of pharmacophore strategy of drug design and developed a new pharmacophore. We have also designed a scheme for synthesizing such pharmacophore and performed their pharmacological screening for the protection of seizures, behavioral study and CNS activity. The compound 1-[1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl) allylidene]-4-(2-fluorophenyl) semicarbazide (8) emerged as the most active prototype molecule in all the models.