125040-04-2

Basic information

• Product Name: Phosphonic acid, [4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxobutyl]-, dimethyl ester
• CAS NO: 125040-04-2
• Molecular Formula: C14H16NO6P
• Molecular Weight: 325.258
• Mol File: 125040-04-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxobutyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxobutyl]-, dimethyl ester(125040-04-2)
• EPA Substance Registry System: Phosphonic acid, [4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxobutyl]-, dimethyl ester(125040-04-2)

Safety Data

• Hazardous Substances Data: 125040-04-2(Hazardous Substances Data)

Upstream product

• 101-02-0 triphenyl phosphite 
• 10314-06-4 4-phthalimidobutyryl chloride 

Downstream Products

• 948317-75-7 [4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-(hydroxy-phenoxy-phosphoryl)butyl]phosphonic acid 

Relevant articles and documents

SYNTHESE D'α CETOPHOSPHONATES ET D'ESTERS D'HYDROXY METHYLENE DIPHOSPHONATES III

The phenylacetic chloride reacts with the trimethyl phosphite an the methoxy tetramethyl dioxaphospholane to give hydroxyvinyl phosphonates 1 and 6 which are starting products in the synthesis of diphosphonates 11 and 16.The reactions of crotonyl chloride a; trans cynnamoyl chloride b; dimethyl acroyl chloride d with the same phosphites are also studied.Stable spirophosphoranes 26', 29 and 25' are obtained from methoxy tetramethyl dioxaphospholane and a, b, c, respectively; d leads quantitatively to the formation of a stable keto phosphonate 27.Keywords: Methoxy tetramethyldioxaphospholane, reaction with carbonacid chlorides, α-ketophosphonates, Hydroxymethylenediphosphonate esters, Stable spirophosphoranes.