125070-46-4Relevant articles and documents
Hydroxy containing amines as phospholipase A2 inhibitors
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, (2008/06/13)
There are disclosed compounds of the formula STR1 R is --CH2 OH or --CO2 R3 ; R1 is hydrogen, lower alkyl, lower alkoxy or hydroxybenzyl; R2 is hydroxyloweralkyl or diloweralkoxyalkyl; R3 is hydrogen or lower alkyl; R4 is alkyl of 10-20 carbons atoms, phenylalkyl of 11-18 carbon atoms or phenoxyalkyl of 11-18 carbon atoms; or n is 1-3; or a pharmaceutically acceptable salt thereof, and their use in the prevention and/or treatment of conditions such as allergic rhinitis, allergic bronchial asthma and other naso-bronchial obstructive air-passageway conditions, other immediate hypersensitivity reactions such as allergic conjunctivitis and various inflammatory conditions.