125094-89-5Relevant articles and documents
One-pot synthesis of 2-morpholino-4-phenylbicyclononanones
Ravishankar, Lakshmy,Trivedi, Girish Kumar
, p. 303 - 307 (2007/10/02)
Condensation of 1-morpholinocyclohexene with cinnamaldehyde in the presence of either Eu(fod)3 or CeCl3 gives 2-morpholino-4-phenylbicyclononan-9-one (4) as the major product.Three other minor products formed in the CeCl3 catalysed reaction have been isolated by column chromatography using pyridine deactivated silica gel as the adsorbent.The CeCl3 catalysed condensation has also been extended to the one-pot synthesis of bicyclic compounds 4a-e and 5.