1250999-09-7

Basic information

• Product Name: 4-(2-fluoro-4-iodophenyl)morpholine
• Synonyms: 4-(2-fluoro-4-iodophenyl)morpholine
• CAS NO: 1250999-09-7
• Molecular Weight: 307.106
• Mol File: 1250999-09-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(2-fluoro-4-iodophenyl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-fluoro-4-iodophenyl)morpholine(1250999-09-7)
• EPA Substance Registry System: 4-(2-fluoro-4-iodophenyl)morpholine(1250999-09-7)

Safety Data

• Hazardous Substances Data: 1250999-09-7(Hazardous Substances Data)

Upstream product

• 93246-53-8 3-fluoro-4-(morpholinyl)aniline 
• 459408-52-7 2-fluorophenyl diethylcarbamate 
• 367-12-4 2-fluorophenol 
• 108-95-2 phenol 
• 66950-63-8 phenyl N,N-dimethylsulfamate 
• 1201594-21-9 C₈H₁₀FNO₃S 

Downstream Products

• 168828-84-0 (R)-5-azidomethyl-3-(3-fluoro-4-(morpholin-4-yl)phenyl)oxazolidin-2-one 
• 165800-03-3 linezolid 
• 1613057-71-8 (4R,5R)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)-4-(4-methoxyphenyl)oxazolidin-2-one 
• 1613057-72-9 3-(((4R,5R)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)-2-oxooxazolidin-5-yl)methoxy)-3-oxopropyl acrylate 
• 1613057-73-0 ((4R,5R)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)-2-oxooxazolidin-5-yl)methyl benzoate 
• 1613057-75-2 (4R,5S)-3-(3-fluoro-4-morpholinophenyl)-5-(hydroxymethyl)-4-(4-methoxyphenyl)oxazolidin-2-one 
• 1613057-76-3 ((4R,5S)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)-2-oxooxazolidin-5-yl)methyl benzoate 
• 1613057-77-4 3-(((4R,5S)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)-2-oxooxazolidin-5-yl)methoxy)-3-oxopropyl acrylate 
• 1613057-78-5 (4R,5R)-5-ethyl-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl) oxazolidin-2-one 
• 1613057-79-6 (4R,5R)-3-(3-fluoro-4-morpholinophenyl)-5-(2-hydroxyethyl)-4-(4-methoxyphenyl)oxazolidin-2-one 
• 1613057-80-9 (4R, 5R)-5-(azidomethyl)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)oxazolidin-2-one 
• 1613057-81-0 (4R,5R)-5-(aminomethyl)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)oxazolidin-2-one 
• 1613057-82-1 N-(((4R,5R)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1613057-74-1 (4R,5R)-3-(3-fluoro-4-morpholinophenyl)-4-(4-methoxyphenyl)-5-vinyloxazolidin-2-one 

Relevant articles and documents

Oxazolidinone derivatives: Cytoxazone-Linezolid hybrids induces apoptosis and senescence in DU145 prostate cancer cells

In this study, we report the synthesis of novel oxazolidinone derivatives derived from linezolid 3 having p-methoxyphenyl group at C-4 position. In vitro evaluation for their anticancer activity toward cultured A549, DU145, HELA, and MCF7 were carried out

Nickel-catalyzed amination of aryl sulfamates

Broad in scope: The first amination of aryl sulfamates, which are attractive cross-coupling partners, particularly for multistep syntheses, was achieved by using a nickel catalyst. The method provides a versatile means to use simple derivatives of phenol as precursors to polysubstituted aryl amines, as exemplified by a concise synthesis of the antibacterial drug linezolid (see scheme).