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125103-48-2

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125103-48-2 Usage

Chemical class

Pyrazole derivatives

Biological activity

Selective and potent inhibitor of histone H3K79 methyltransferase DOT1L

Involvement in gene transcription

Plays a role in the process of gene transcription

Therapeutic applications

Potential treatment for leukemia and other cancers

Development

Epigenetic therapies

Chemical structure

Consists of a pyrazole ring and phenyl and methylbutyl substituents

Research and development

Promising candidate for further research in medicinal chemistry and drug discovery
These properties and contents provide a comprehensive overview of A-366, highlighting its potential as a therapeutic agent and its significance in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 125103-48-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,1,0 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 125103-48:
(8*1)+(7*2)+(6*5)+(5*1)+(4*0)+(3*3)+(2*4)+(1*8)=82
82 % 10 = 2
So 125103-48-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H25N3O/c1-16(2)14-15-23-22(26)20-17(3)25(19-12-8-5-9-13-19)24-21(20)18-10-6-4-7-11-18/h4-13,16H,14-15H2,1-3H3,(H,23,26)

125103-48-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-N-(3-methylbutyl)-1,3-diphenylpyrazole-4-carboxamide

1.2 Other means of identification

Product number -
Other names 1H-Pyrazole-4-carboxamide,5-methyl-N-(3-methylbutyl)-1,3-diphenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:125103-48-2 SDS

125103-48-2Downstream Products

125103-48-2Relevant articles and documents

SEARCH FOR ANTIALCOHOLIC AGENTS IN THE SERIES OF AMIDES OF SUBSTITUTED PYRAZOLE-4-CARBOXYLIC AND PYRAZOLE-4-ACETIC ACIDS

Zagorevskii, V. A.,Vlasova, N. V.,Zykov, D. A.,Kirsanova, Z. D.

, p. 684 - 689 (2007/10/02)

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