1251537-48-0 Usage
General Description
1-Benzyl-piperidine-4-boronic acid is a chemical compound that is commonly used in organic synthesis and medicinal chemistry. It is an organoboronic acid derivative that contains a piperidine ring with a benzyl group attached to it. The boronic acid functionality makes it a useful reagent for Suzuki-Miyaura cross-coupling reactions, which are important in the synthesis of complex organic molecules. Additionally, the piperidine ring is commonly found in many pharmaceuticals and bioactive compounds, making this compound a valuable intermediate in drug discovery and development. Overall, 1-benzyl-piperidine-4-boronic acid plays a significant role in the field of organic chemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 1251537-48-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,1,5,3 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1251537-48:
(9*1)+(8*2)+(7*5)+(6*1)+(5*5)+(4*3)+(3*7)+(2*4)+(1*8)=140
140 % 10 = 0
So 1251537-48-0 is a valid CAS Registry Number.
1251537-48-0Relevant articles and documents
A General C(sp3)-C(sp3) Cross-Coupling of Benzyl Sulfonylhydrazones with Alkyl Boronic Acids
Merchant, Rohan R.,Lopez, Jovan A.
supporting information, p. 2271 - 2275 (2020/03/13)
A general transition-metal-free cross-coupling between benzylic sulfonylhydrazones and 1°, 2°, or 3° alkyl boronic acids is reported. The base-promoted reaction is operationally simple and exhibits a broad substrate scope to forge a variety of alkyl-alkyl bonds, including between sterically encumbered secondary and tertiary sp3-carbons. The ability of this method to simplify retrosynthetic analysis is exemplified by the improved synthesis of multiple medicinally relevant scaffolds.
INHIBITORS OF FATTY ACID AMIDE HYDROLASE
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Page/Page column 71, (2010/11/03)
Provided herein are compounds of formula (I): or pharmaceutically acceptable salts, solvates or prodrugs thereof or mixtures thereof, wherein Z1, Z2, X1, X2, X3, R1, R2 R3/
