125173-71-9Relevant articles and documents
Novel 21-Aminosteroids That Inhibit Iron-Dependent Lipid Peroxidation and Protect against Central Nervous System Trauma
Jacobsen, E. Jon,McCall, John M.,Ayer, Donald E.,VanDoornik, Fred J.,Palmer, John R.,et al.
, p. 1145 - 1151 (1990)
A novel class of 21-aminosteroids has been developed.Compounds within this series are potent inhibitors of iron-dependent lipid peroxidation in rat brain homogenates with IC50's as low as 3 μM.Furthermore, selected members enhance early neurolo