125226-39-3

Basic information

• Product Name: 6-ethoxydihydrochelerythrine
• CAS NO: 125226-39-3
• Molecular Weight: 393.439
• Mol File: 125226-39-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-ethoxydihydrochelerythrine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-ethoxydihydrochelerythrine(125226-39-3)
• EPA Substance Registry System: 6-ethoxydihydrochelerythrine(125226-39-3)

Safety Data

• Hazardous Substances Data: 125226-39-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 3895-92-9 chelerythrine chloride 
• 141-52-6 sodium ethanolate 
• 34316-15-9 chelerythrinium 

Relevant articles and documents

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In vitro antifungal activity of sanguinarine and chelerythrine derivatives against phytopathogenic fungi

In order to understand the antifungal activity of some derivatives of sanguinarine (S) and chelerythrine (C) and their structure-activity relationships, sixteen derivatives of S and C were prepared and evaluated for in vitro antifungal activity against seven phytopathogenic fungi by the mycelial growth rate method. The results showed that S, C and their 6-alkoxy dihydro derivatives S1-S4, C1-C4 and 6-cyanodihydro derivatives S5, C5 showed significant antifungal activity at 100 μg/mL against all the tested fungi. For most tested fungi, the median effective concentrations of S, S1, C and C1 were in a range of 14-50 μg/mL. The structure-activity relationship showed that the C=N+ moiety was the determinant for the antifungal activity of S and C. S1-S5 and C 1-C5 could be considered as the precursors of S and C, respectively. Thus, the present results strongly suggested that S and C or their derivatives S1-S5 and C1-C5 should be considered as good lead compounds or model molecules to develop new anti-phytopathogenic fungal agents.