1252553-12-0

Basic information

• Product Name: 17-oximino-5-androsten-3β-yl phenylacetate
• Synonyms: 17-oximino-5-androsten-3β-yl phenylacetate
• CAS NO: 1252553-12-0
• Molecular Weight: 421.58
• Mol File: 1252553-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 17-oximino-5-androsten-3β-yl phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 17-oximino-5-androsten-3β-yl phenylacetate(1252553-12-0)
• EPA Substance Registry System: 17-oximino-5-androsten-3β-yl phenylacetate(1252553-12-0)

Safety Data

• Hazardous Substances Data: 1252553-12-0(Hazardous Substances Data)

Upstream product

• 512-04-9 diosgenin 
• 979-02-2 16-dehydropregnenolone acetate 
• 23549-24-8 3β-acetoxy-20-hydroxyiminopregna-5,16-diene 
• 853-23-6 prasterone acetate 
• 103-82-2 phenylacetic acid 
• 1232-19-5 17-hydroxyiminoandrost-5-en-3β-ol 

Relevant articles and documents

17-Oximino-5-androsten-3β-yl esters: Synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level

The 17-oximino-5-androsten-3β-yl esters (10a- 10j) were synthesized from commercially available (25R)- 5-Spirosten-3β-ol (Diosgenin) (4) as starting material. The synthesized compounds were evaluated for their antiproliferative activity against prostate specific cancer cell line DU-145, acute toxicity, and effect on serum androgen level and were compared with Finasteride used as positive control. Some of the compounds exhibited better cytotoxicity and antiandrogenic activity than the reference control. The detailed synthesis, spectroscopic data, and biological evaluation for the synthesized compounds are reported. Springer Science+Business Media, LLC 2010.