1253282-57-3Relevant articles and documents
Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases
Daher, Racha,Coin?on, Mathieu,Fonvielle, Matthieu,Gest, Petra M.,Guerin, Marcelo E.,Jackson, Mary,Sygusch, Jurgen,Therisod, Michel
supporting information; experimental part, p. 7836 - 7842 (2011/02/24)
We report the synthesis and biochemical evaluation of several selective inhibitors of class II (zinc dependent) fructose bis-phosphate aldolases (Fba). The products were designed as transition-state analogues of the catalyzed reaction, structurally relate