1253293-38-7

Basic information

• Product Name: 1-(4-hydroxy-phenyl)-heptane-1,3-dione 3-[O-(4-nitro-phenyl)-oxime]
• Synonyms: 1-(4-hydroxy-phenyl)-heptane-1,3-dione 3-[O-(4-nitro-phenyl)-oxime]
• CAS NO: 1253293-38-7
• Molecular Weight: 356.378
• Mol File: 1253293-38-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(4-hydroxy-phenyl)-heptane-1,3-dione 3-[O-(4-nitro-phenyl)-oxime](CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-hydroxy-phenyl)-heptane-1,3-dione 3-[O-(4-nitro-phenyl)-oxime](1253293-38-7)
• EPA Substance Registry System: 1-(4-hydroxy-phenyl)-heptane-1,3-dione 3-[O-(4-nitro-phenyl)-oxime](1253293-38-7)

Safety Data

• Hazardous Substances Data: 1253293-38-7(Hazardous Substances Data)

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 624-24-8 methyl valerate 
• 109-92-2 ethyl vinyl ether 
• 1137261-89-2 1-(4-hydroxy-phenyl)-heptane-1,3-dione 
• 33543-55-4 p-nitrophenoxyamine 

Downstream Products

• 141645-16-1 2-n-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran 

Relevant articles and documents

PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS

The present invention relates to a process for the preparation of a compound of formula wherein R1 is selected from C1-6-alkyl, C3-6-cycloalkyl and aralkyl, and wherein R2 at each occurrence independently is halogen or C1-6-alkyl, and m is an integer from 0 to 4, Q is selected from halogen, —NO2 and —NR3R4, wherein R3 and R4 are independently selected from hydrogen, C1-6-alkyl, C3-6-cycloalkyl, aryl, aralkyl, mesyl and tosyl, or wherein R3 and R4 together form a C4-6-alkylene group, Y at each occurrence is hydrogen or a hydroxy protection group W that can be hydrolytically cleaved under acidic conditions, and n is an integer from 1 to 3, and n is an integer from 1 to 3, with the proviso that n and m together are not greater than 5.

NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS

There is provided a process for the preparation of a compound of formula (II), wherein R1, R2, R3 and R4 are as described in the description. Such compounds may, for example, be useful intermediates in the synthesis of drugs such as Dronedarone.

Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans

The present invention relates to a process for the preparation of a compound of formula wherein R1 is selected from C1-6-alkyl, C3-6-cycloalkyl and aralkyl, and wherein R2 at each occurrence independently is halogen or C1-6-alkyl, and m is an integer from 0 to 4, Q is selected from halogen, -NO2 and -NR3R4, wherein R3 and R4 are independently selected from hydrogen, C1-6-alkyl, C1-6-cycloalkyl, aryl, aralkyl, mesyl and tosyl, or wherein R3 and R4 together form a C4-6-alkylene group, Y at each occurrence is hydrogen or a hydroxy protection group W that can be hydrolytically cleaved under acidic conditions, and n is an integer from 1 to 3, and n is an integer from 1 to 3, with the proviso that n and m together are not greater than 5.