1253383-98-0

Basic information

• Product Name: 2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}-5-fluorobenzoic acid
• Synonyms: 2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}-5-fluorobenzoic acid
• CAS NO: 1253383-98-0
• Molecular Weight: 324.352
• Mol File: 1253383-98-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}-5-fluorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}-5-fluorobenzoic acid(1253383-98-0)
• EPA Substance Registry System: 2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}-5-fluorobenzoic acid(1253383-98-0)

Safety Data

• Hazardous Substances Data: 1253383-98-0(Hazardous Substances Data)

Upstream product

• 2991-28-8 2,5-difluorobenzoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1197193-39-7 5-fluoro-2-(piperazin-1-yl)benzoic acid 
• 1253383-99-1 4-(4-fluoro-2-methoxycarbonyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure relates to compounds of formula (I') and pharmaceutical compositions and their use in reducing Widely Interspaced Zinc Finger Motifs (WIZ) expression levels, or inducing fetal hemoglobin (HbF) expression, and in the treatment of inherited blood disorders (e.g., hemoglobinopathies, e.g., beta-hemoglobinopathies), such as sickle cell disease and beta-thalassemia.

CXCR3 RECEPTOR ANTAGONISTS

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 to R6, A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.