125367-35-3

Basic information

• Product Name: N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester
• Synonyms: 5,5'-Dinitro-BAPTA-tetraMethyl Ester;N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester
• CAS NO: 125367-35-3
• Molecular Formula: C26H30N4O14
• Molecular Weight: 622.5348
• Product Categories: Amines;Aromatics;Chelating Agents & Ligands;Fluorescent Labels & Indicators;Amines, Aromatics, Chelating Agents & Ligands, Fluorescent Labels & Indicators
• Mol File: 125367-35-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester(125367-35-3)
• EPA Substance Registry System: N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester(125367-35-3)

Safety Data

• Hazardous Substances Data: 125367-35-3(Hazardous Substances Data)

Usage

Description

N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester, also known as a nitrated tetramethyl ester derivative of BAPTA (B123500), is a highly selective calcium chelating reagent. It is characterized by its ability to bind calcium ions with high specificity, making it a valuable compound in various scientific and medical applications.

Uses

Used in Research and Development:
N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester is used as a key component in the preparation of lipophilic calcium-sensitive fluorescent dyes. These dyes are essential for the characterization of calcium translocation across the plasma membrane, which is a critical process in various cellular functions and signaling pathways.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester is used as a starting material for the development of drugs targeting calcium-related disorders. Its high selectivity for calcium ions allows for the creation of targeted therapies with minimal side effects.
Used in Diagnostics:
N,N'-[1,2-Ethanediylbis[oxy(4-nitro-2,1-phenylene)]]bis[N-(2-Methoxy-2-oxoethyl)glycine DiMethyl Ester is also utilized in the development of diagnostic tools that measure calcium levels in biological samples. These tools can be used to detect and monitor various conditions related to calcium imbalance, such as hypercalcemia and hypocalcemia.