1253786-22-9

Basic information

• Product Name: 2-tert-butyl-1-(4-methoxyphenyl)-1,2-dihydronaphtho[1,2-d]isoxazole
• CAS NO: 1253786-22-9
• Molecular Weight: 333.43
• Mol File: 1253786-22-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butyl-1-(4-methoxyphenyl)-1,2-dihydronaphtho[1,2-d]isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butyl-1-(4-methoxyphenyl)-1,2-dihydronaphtho[1,2-d]isoxazole(1253786-22-9)
• EPA Substance Registry System: 2-tert-butyl-1-(4-methoxyphenyl)-1,2-dihydronaphtho[1,2-d]isoxazole(1253786-22-9)

Safety Data

• Hazardous Substances Data: 1253786-22-9(Hazardous Substances Data)

Upstream product

• 43052-01-3 2-tert-butyl-3-(4-methoxyphenyl)-1,2-oxaziridine 

Relevant articles and documents

Synthesis of dihydrobenzisoxazoles by the [3 + 2] cycloaddition of arynes and oxaziridines

Dihydrobenzisoxazoles are readily prepared in good yields by the [3 + 2] cycloaddition of oxaziridines and arynes. The reaction involves an unusual cleavage of the C-O bond of the oxaziridine and tolerates a variety of substituents on the oxaziridine and the o-(trimethylsilyl)aryl triflate to form aryl-, heteroaryl-, alkyl-, and naphthyl-substituted dihydrobenzisoxazoles. The resulting halogen-substituted dihydrobenzisoxazoles are readily elaborated to more complex products using palladium-catalyzed crossing-coupling processes.