1254975-19-3

Basic information

• Product Name: pregabalin phtalic imide
• Synonyms: pregabalin phtalic imide
• CAS NO: 1254975-19-3
• Molecular Weight: 289.331
• Mol File: 1254975-19-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: pregabalin phtalic imide(CAS DataBase Reference)
• NIST Chemistry Reference: pregabalin phtalic imide(1254975-19-3)
• EPA Substance Registry System: pregabalin phtalic imide(1254975-19-3)

Safety Data

• Hazardous Substances Data: 1254975-19-3(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 148553-50-8 pregabilin 

Relevant articles and documents

Visible-Light-Promoted Activation of Unactivated C(sp3)-H Bonds and Their Selective Trifluoromethylthiolation

Selective functionalization of ubiquitous C(sp3)-H bonds using visible light is a highly challenging yet desirable goal in organic synthesis. The development of such processes relies on both rational design and serendipitous discoveries from innovative tools such as screening technologies. Applying a mechanism-based screening strategy, we herein report photoredox-mediated hydrogen atom transfer catalysis for the selective activation of otherwise unactivated C(sp3)-H bonds, followed by their trifluoromethylthiolation, which has high potential as a late-stage functionalization tool. The generality of this method is exhibited through incorporation of the trifluoromethylthio group in a large number of C(sp3)-H bonds with high selectivity without the need for an excess of valuable substrate.