1254982-53-0Relevant articles and documents
Construction of a spirooxindole amide library through nitrile hydrozirconation-acylation-cyclization cascade
Laporte, Matthew G.,Tsegay, Sammi,Hong, Ki Bum,Lu, Chunliang,Fang, Cheng,Wang, Lirong,Xie, Xiang-Qun,Floreancig, Paul E.
, p. 344 - 349 (2013/07/26)
A library of spirooxindoles containing varied elements of structural and stereochemical diversity has been constructed via a three step, one pot nitrile hydrozirconation-acylation-cyclization reaction sequence from common acyclic indole intermediates. The resulting library was evaluated for novelty through comparison with MLSMR and Maybridge compound collections.