125500-66-5

Basic information

• Product Name: 3-butyryl-4-(4-fluoro-2-methylphenyl-amino)-8-hydroxyquinoline
• Synonyms: 3-butyryl-4-(4-fluoro-2-methylphenyl-amino)-8-hydroxyquinoline
• CAS NO: 125500-66-5
• Molecular Weight: 338.381
• Mol File: 125500-66-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-butyryl-4-(4-fluoro-2-methylphenyl-amino)-8-hydroxyquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-butyryl-4-(4-fluoro-2-methylphenyl-amino)-8-hydroxyquinoline(125500-66-5)
• EPA Substance Registry System: 3-butyryl-4-(4-fluoro-2-methylphenyl-amino)-8-hydroxyquinoline(125500-66-5)

Safety Data

• Hazardous Substances Data: 125500-66-5(Hazardous Substances Data)

Upstream product

• 452-71-1 4-fluor-2-methylaniline 
• 10097-32-2 bromine 
• 144-55-8 sodium hydrogencarbonate 
• 115607-76-6 3-butyryl-4-chloro-8-methoxyquinoline 
• 125500-45-0 3-butyryl-4-chloro-8-hydroxyquinoline 
• 115607-74-4 2-[1-(2-Methoxy-phenylamino)-meth-(Z)-ylidene]-3-oxo-hexanoic acid ethyl ester 
• 115607-75-5 3-butyryl-8-methoxy-4(1H)-quinolone 
• 125500-84-7 ethyl 2-(ethoxymethylene)-3-oxohexanoate 
• 3249-68-1 ethyl butyroyl acetate 
• 90-04-0 2-methoxy-phenylamine 

Relevant articles and documents

Reversible inhibitors of the gastric (H+/K+)-ATPase. 4. Identification of an inhibitor with an intermediate duration of action

3-Acyl-4-(arylamino)quinolines were previously identified as gastric (H+/K+)-ATPase inhibitors, and clinical efficacy has been demonstrated for compound 3 (SK and F 96067). In the present study the further structure- activity relatio

Substituted 4-aminoquinoline derivatives as gastric acid secretion inhibitors

Substituted 4-aminoquinazoline derivatives of the formula: STR1 in which R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy, C1-6 alkoxyC1-6 alkyl, C3-6 cycloalkyl, C3-6 cycloalkylC1-6 alkyl, phenylC1-6 alkyl, the phenyl group being optionally substituted; R2 is hydrogen, C1-6 alkyl, C1-6 alkoxy, amino, C1-6 alkylthio, halogen, cyano, hydroxy, carbamoyl, carboxy, C1-6 alkanoyl or trifluoromethyl; m is 1 to 3; p is 0 to 4; R3 is COR4 ; R4 is hydroxy, C1-6 alkoxy, or NR5 R6 ; R5 and R6 are each hydrogen or C1-6 alkyl or together with the nitrogen atom to which they are attached form a heterocyclic ring; and R7 is hydrogen, C1-6 alkoxy or C1-6 alkyl; or a salt thereof.