1255312-77-6

Basic information

• Product Name: 3-(tert-butyl-diphenylsilanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine
• Synonyms: 3-(tert-butyl-diphenylsilanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine
• CAS NO: 1255312-77-6
• Molecular Weight: 493.742
• Mol File: 1255312-77-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(tert-butyl-diphenylsilanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(tert-butyl-diphenylsilanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine(1255312-77-6)
• EPA Substance Registry System: 3-(tert-butyl-diphenylsilanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine(1255312-77-6)

Safety Data

• Hazardous Substances Data: 1255312-77-6(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 85310-69-6 pyrrolidin-3-ylmethanol 

Relevant articles and documents

Iron(III)-catalyzed consecutive aza-cope-mannich cyclization: Synthesis of trans -3,5-dialkyl pyrrolidines and 3,5-dialkyl-2,5-dihydro-1 H-pyrroles

An efficient alkene aza-Cope-Mannich cyclization between 2-hydroxy homoallyl tosylamine and aldehydes in the presence of iron(III) salts to obtain 3-alkyl-1-tosyl pyrrolidines in good yields is described. The process is based on the consecutive generation of a γ-unsaturated iminium ion, 2-azonia-[3,3]-sigmatropic rearrangement, and further intramolecular Mannich reaction. Iron(III) salts are also shown to be excellent catalysts for the new aza-Cope-Mannich cyclization using 2-hydroxy homopropargyl tosylamine.