1255365-30-0

Basic information

• Product Name: 2-methyl-N-morpholinobenzenesulfonamide
• Synonyms: 2-methyl-N-morpholinobenzenesulfonamide
• CAS NO: 1255365-30-0
• Molecular Weight: 256.326
• Mol File: 1255365-30-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-methyl-N-morpholinobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-N-morpholinobenzenesulfonamide(1255365-30-0)
• EPA Substance Registry System: 2-methyl-N-morpholinobenzenesulfonamide(1255365-30-0)

Safety Data

• Hazardous Substances Data: 1255365-30-0(Hazardous Substances Data)

Upstream product

• 4319-49-7 1-aminomorpholine 
• 615-37-2 ortho-methylphenyl iodide 
• 16419-60-6 2-Methylphenylboronic acid 
• 2093-46-1 2-methylphenyl diazonium tetrafluoroborate 
• 18412-55-0 triethoxy(o-tolyl)silane 
• 95-53-4 o-toluidine 
• 36719-44-5 3,3-diethyl-1-(o-tolyl)triaz-1-ene 
• 42096-33-3 o-tolyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 

Relevant articles and documents

A palladium-catalyzed coupling reaction of aryl nonaflates, sulfur dioxide, and hydrazines

A facile route to synthesise N-aminosulfonamides through a palladium-catalyzed coupling reaction of aryl nonaflates, sulfur dioxide, and hydrazines is reported. This transformation proceeds in the presence of Pd(OAc)2/XantPhos, and TBAB in 1,4-dioxane at 80°C, leading to the corresponding N-aminosulfonamides in moderate to good yields. The reaction scope has been demonstrated, and good functional tolerance is observed. A plausible mechanism is proposed through the insertion of sulfur dioxide.

Catalytic conversion of aryl triazenes into aryl sulfonamides using sulfur dioxide as the sulfonyl source

Various sulfonamides have been synthesized from triazenes and sulfur dioxide. In the presence of just a catalytic amount of BF3· OEt2, a series of 1-aryl-triazenes were converted into sulfonyl hydrazines in good to excellent yields. When using CuCl2 as the catalyst, the corresponding sulfonamides can be produced from the 1-aryl triazenes in good yields. This journal is the Partner Organisations 2014.

Metal-free aminosulfonylation of aryldiazonium tetrafluoroborates with DABCO×(SO2)2 and hydrazines

The coupling of aryldiazonium tetrafluoroborates, DABCO×(SO 2)2, and hydrazines under metal-free conditions leads to the formation of aryl N-aminosulfonamides. The reaction proceeds smoothly at room temperature and shows broad functional-group tolerance. A radical process is proposed for this transformation. The coupling of aryldiazonium tetrafluoroborates, DABCO×(SO2)2, and hydrazines under metal-free conditions leads to the formation of aryl N-aminosulfonamides. The reaction proceeds under mild reaction conditions, is fast, has a broad substrate scope, and gives the products in high yiels (21 examples). A plausible mechanism that involves a radical process is also proposed. Copyright