1255716-52-9Relevant articles and documents
A new convenient synthesis of some novel 2,6-disubstituted-pyridine derivatives
Ali, Korany A.
experimental part, p. 55 - 63 (2010/12/20)
The versatile, hitherto unreported pyridine-2,6-bis-(3-oxo-3- propanenitrile) 2 was prepared by the Claisen condensation of pyridine-2,6-dicarboxylic acid ester 1 with acetonitrile in the presence of sodium hydride. Several new pyrazoles, isoxazoles, and pyrazolopyridazine derivatives have been synthesized by the reaction of pyridine-2,6-bis-(3-oxo-3- propanenitrile) 2 with bidentate nucleophilic reagents and hydrazonoyl chloride derivatives. ARKAT USA, Inc.