125582-80-1Relevant articles and documents
A synthetic strategy toward eight-membered cyclic amines by cycloetherification and claisen rearrangement
Han, Seo-Jung,Cavitt, Marchello A.,Stoltz, Brian M.
, p. 3300 - 3303 (2021)
Eight-membered nitrogen-containing heterocycles were straightforwardly produced by a nickel-catalyzed cycloetherification and subsequent Claisen rearrangement of secondary and tertiary alcohols. In particular, a one-pot transformation was achieved with tertiary alcohols in moderate to good yields. This operationally simple reaction is tolerant of many functional groups and applicable to the synthesis of various medium-sized ring nitrogen-containing heterocycles.
AMINOLEAD COMPOUNDS AS A NEW REAGENT FOR REGIOSELECTIVE RING OPENING OF EPOXIDES
Yamada, Jun-ichi,Yumoto, Masatoshi,Yamamoto, Yoshinori
, p. 4255 - 4258 (2007/10/02)
Regioselective ring opening of epoxides is accomplished by using aminolead compounds; the reagents attack the less hindered carbon of epoxide ring, and the amino alcohols are obtained in good yields.
