1256-06-0Relevant articles and documents
THE USE OF LIPOPHILIC BETA-LACTAM ANTIBIOTICS AND CARBOXYLATE ESTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS WITHIN CITRUS AND OTHER PLANT SPECIES
-
Paragraph 0035-0036; 0039; 0048, (2020/08/05)
Disclosed is method for converting a beta-lactam antibiotic into a “masked” beta-lactam antibiotic to permit it to cross the waxy cuticle of a plant and then subsequently unmasking the beta-lactam and converting it into an active beta-lactam antibiotic in
Wittig Reactions with β-Lactam Carbonyl Functions. The Effect of C-7 Substitution on the Chemistry of Penicillins and Clavulanic Acid Derivatives.
Gilpin, Martin L.,Harbridge, John B.,Howarth, T. Trefor
, p. 1369 - 1376 (2007/10/02)
The Wittig reaction of phosphoranes and phosphonates with the carbonyl function of mono- and bicyclic β-lactams has been studied and the inluence of phosphorane and β-lactam reactivities on the outcome of the reaction noted.The utility and general chemist
THE SYNTHESIS OF L-α-AMINOADIPYL-L-CYSTEINYL-D-3,4-DIDEHYDROVALINE, A POTENT INHIBITOR OF ISOPENICILLIN SYNTHETASE
Baldwin, Jack E.,Chakravarti, Bulbul,Field, Leslie D.,Murphy, John A.,Whitten, Kathy R.,et al.
, p. 2773 - 2776 (2007/10/02)
The title peptide (1) has been synthesized and incubated with an active cell-free extract of Cephalosporium acremonium, no conversion to active antibiotics was observed; however on co-incubation with the Arnstein tripeptide (ACV) (2), strong inhibition of