125600-42-2Relevant articles and documents
A dramatic enhancing effect of InBr3 towards the oxidative Sonogashira cross-coupling reaction of 2-ethynylanilines
Ikeda,Omote,Kusumoto,Komori,Tarui,Sato,Ando
, p. 2127 - 2133 (2016/02/18)
The addition of InBr3 to the oxidative Sonogashira cross-coupling reaction of 2-ethynylaniline with (E)-trimethyl(3,3,3-trifluoroprop-1-enyl)silane led to a dramatic increase in the reactivity to afford the corresponding 1,3-enynes bearing a trifluoromethyl group on their terminal sp2 carbon. The subsequent cyclization of these 1,3-enynes under palladium catalysis provides access to the corresponding indoles bearing a 3,3,3-trifluoroprop-1-enyl group at their 2-position.
[Cp*IrCl2]2 catalyzed formation of 2,2′-biindoles from 2-ethynylanilines
Kumaran, Elumalai,Fan, Wai Yip,Leong, Weng Kee
, p. 1342 - 1345 (2014/04/03)
[Cp*IrCl2]2 catalyzes the cyclization of 2-ethynylanilines to 2,2′-biindoles via intramolecular hydroamination. A reaction pathway has been proposed on the basis of deuterium labeling experiments and computational studies.
Copper-catalyzed [5 + 1] annulation of 2-ethynylanilines with an N, O -acetal leading to construction of quinoline derivatives
Sakai, Norio,Tamura, Kosuke,Shimamura, Kazuyori,Ikeda, Reiko,Konakahara, Takeo
supporting information; experimental part, p. 836 - 839 (2012/04/05)
A novel copper-catalyzed [5 + 1] annulation of 2-ethynylanilines with an N,O-acetal, which functioned as a C1 part, leading to the preparation of quinoline derivatives with an ester substituent on the 2-position is described. A combination of CuBr2/
