1256354-66-1Relevant articles and documents
Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors
Song, Hyunmin,Oh, Sei-Ryang,Lee, Hyeong-Kyu,Han, Gyoonhee,Kim, Joo-Heon,Chang, Hyeun Wook,Doh, Kyung-Eun,Rhee, Hee-Kyung,Choo, Hea-Young Park
experimental part, p. 7580 - 7585 (2011/01/04)
5-Lipoxygenase (5-LOX) is important enzyme in the biosynthesis of leukotrienes, and is a potential target in the treatment of asthma and allergy. We designed and synthesized a series of benzoxazoles and benzothiazoles as 5-LOX inhibitors. Fourteen compoun