125641-00-1

Basic information

• Product Name: Butanoic acid, 2-diazo-3-oxo-, 2,6-bis(1,1-dimethylethyl)-4-methylphenyl ester
• CAS NO: 125641-00-1
• Molecular Formula: C19H26N2O3
• Molecular Weight: 330.427
• Mol File: 125641-00-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-diazo-3-oxo-, 2,6-bis(1,1-dimethylethyl)-4-methylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-diazo-3-oxo-, 2,6-bis(1,1-dimethylethyl)-4-methylphenyl ester(125641-00-1)
• EPA Substance Registry System: Butanoic acid, 2-diazo-3-oxo-, 2,6-bis(1,1-dimethylethyl)-4-methylphenyl ester(125641-00-1)

Safety Data

• Hazardous Substances Data: 125641-00-1(Hazardous Substances Data)

Upstream product

• 674-82-8 4-methyleneoxetan-2-one 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 

Downstream Products

• 172977-67-2 2,6-Bis(1,1-dimethylethyl)-4-methylphenyl 3-((1,1-dimethylethyl)dimethylsiloxy)-2-diazo-3-butenoate 
• 125641-41-0 (E)-But-2-enedioic acid bis-(2,6-di-tert-butyl-4-methyl-phenyl) ester 
• 125641-40-9 (Z)-But-2-enedioic acid bis-(2,6-di-tert-butyl-4-methyl-phenyl) ester 
• 125641-25-0 (1R,2S)-2-Butyl-cyclopropanecarboxylic acid 2,6-di-tert-butyl-4-methyl-phenyl ester 
• 125641-25-0 2,6-di-tert-butyl-4-methylphenyl trans-2-(n-butyl)cyclopropanecarboxylate 
• 125641-42-1 {[1-(2,6-Di-tert-butyl-4-methyl-phenoxycarbonyl)-meth-(E)-ylidene]-hydrazono}-acetic acid 2,6-di-tert-butyl-4-methyl-phenyl ester 
• 125640-98-4 2,6-di-tert-butyl-4-methylphenyl trans-2-(3-cyclohexen-1-yl)cyclopropanecarboxylate 
• 108546-83-4 2,6-di-tert-butyl-4-methylphenyl trans-2-phenylcyclopropanecarboxylate 
• 125641-39-6 2,6-di-tert-butyl-4-methylphenyl trans-2-(2-methyl-1-propenyl)-3,3-dimethylcyclopropanecarboxylate 
• 125641-36-3 2,6-di-tert-butyl-4-methylphenyl anti-2-oxobicyclo<4.1.0>heptane-7-carboxylate 
• 125640-94-0 2,6-di-tert-butyl-4-methylphenyl 2-cyclopentenylacetate 

Relevant articles and documents

Ethynylbenziodazolones (EBZ) as Electrophilic Alkynylation Reagents for the Highly Enantioselective Copper-Catalyzed Oxyalkynylation of Diazo Compounds

Ethynylbenziodoxol(on)e (EBX) cyclic hypervalent iodine reagents are now established reagents for the alkynylation of radicals and nucleophiles, yet they present limited possibilities for further structure and reactivity modification. Herein, the first synthesis is reported for the corresponding ethynylbenziodazolone (EBZ) reagents, in which the oxygen atom in the iodoheterocycle is replaced by a nitrogen atom. The substituent on the nitrogen enables further fine-tuning of the reagent structure and reactivity. EBZ reagents are obtained easily from the corresponding benzamides by using a one-step procedure, and display reactivity comparable to that of EBX reagents. In particular, they are applied in an asymmetric copper-catalyzed oxyalkynylation of diazo compounds, which proceeds in high yield and enantioselectivity for a broad range of substituents on the diazo compounds and the alkyne.

Exceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactions

Exceptionally high trans (anti) stereoselectivities are obtained in rhodium(II) carboxylate and carboxamide catalyzed alkene cyclopropanation reactions with 2,6-di-tert-butyl-4-methylphenyl diazoacetate (BDA). With monosubstituted ethylenes, use of rhodiu