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1256563-40-2

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1256563-40-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1256563-40-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,5,6 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1256563-40:
(9*1)+(8*2)+(7*5)+(6*6)+(5*5)+(4*6)+(3*3)+(2*4)+(1*0)=162
162 % 10 = 2
So 1256563-40-2 is a valid CAS Registry Number.

1256563-40-2Downstream Products

1256563-40-2Relevant articles and documents

Design and synthesis of selective and potent orally active S1P5 agonists

Mattes, Henri,Dev, Kumlesh Kumar,Bouhelal, Rochdi,Barske, Carmen,Gasparini, Fabrizio,Guerini, Danilo,Mir, Anis Khusro,Orain, David,Osinde, Maribel,Picard, Anne,Dubois, Celine,Tasdelen, Engin,Haessig, Samuel

, p. 1693 - 1696 (2012/01/02)

Putting the brakes on demyelination: Fingolimod (FTY720) was recently shown to significantly decrease relapse rates in patients with multiple sclerosis. This drug attenuates the trafficking of harmful T-cells entering the brain by regulating sphingosine-1-phosphate (S1P) receptors. We designed, synthesized, evaluated 2H-phthalazin-1-one derivatives (e.g., 1L) as selective S1P5 receptor agonists; these compounds are highly potent and selective, with good PK properties, and significant activity in oligodendrocytes. (Chemical Presented).

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